Olmo ED, Barboza B, Delgado-Esteban M et al. Bioorg Chem. 2024 Mar 3;146:107255. doi: 10.1016/j.bioorg.2024.107255. Online ahead of print. PMID: 38457955
Publicaciones
Pharmacological preclinical comparison of tenecteplase and alteplase for the treatment of acute stroke
Correa-Paz C, Pérez-Mato M, Bellemain-Sagnard M et al. J Cereb Blood Flow Metab. 2024 Mar 4:271678X241237427. doi: 10.1177/0271678X241237427. Online ahead of print. PMID: 38436292
Pilot Study Assessing the Safety and Acceptance of a Novel Virtual Reality System to Improve Visual Function
Leal-Vega L, Piñero DP, Molina-Martín A et al. Semin Ophthalmol. 2024 Mar 1:1-6. doi: 10.1080/08820538.2024.2324074. Online ahead of print. PMID: 38426308
Endothelial cells and macrophages as allies in the healthy and diseased brain
Denes A, Hansen CE, Oezorhan U et al. Acta Neuropathol. 2024 Feb 12;147(1):38. doi: 10.1007/s00401-024-02695-0. PMID: 38347307
Endovascular Thrombectomy Treatment Effect in Direct vs Transferred Patients With Large Ischemic Strokes: A Prespecified Analysis of the SELECT2 Trial
Sarraj A, Hill MD, Hussain MS, Abraham MG et al. JAMA Neurol. 2024 Feb 8:e240206. doi: 10.1001/jamaneurol.2024.0206. Online ahead of print. PMID: 38363872
Safety and efficacy of platelet glycoprotein VI inhibition in acute ischaemic stroke (ACTIMIS): a randomised, double-blind, placebo-controlled, phase 1b/2a trial
Mazighi M, Köhrmann M, Lemmens R et al. Lancet Neurol. 2024 Feb;23(2):157-167. doi: 10.1016/S1474-4422(23)00427-1. PMID: 38267188
Systemic biomarker associated with poor outcome after futile reperfusion
Hervella P, Sampedro-Viana A et al. Eur J Clin Invest. 2024 Feb 15:e14181. doi: 10.1111/eci.14181. Online ahead of print. PMID: 38361320
https://pubmed.ncbi.nlm.nih.gov/38361320/
Abstract:
Background: Successful recanalization does not lead to complete tissue reperfusion in a considerable percentage of ischemic stroke patients. This study aimed to identify biomarkers associated with futile recanalization. Leukoaraiosis predicts poor outcomes of this phenomenon. Soluble tumour necrosis factor-like weak inducer of apoptosis (sTWEAK), which is associated with leukoaraiosis degrees, could be a potential biomarker.
Methods: This study includes two cohorts of ischemic stroke patients in a multicentre retrospective observational study. Effective reperfusion, defined as a reduction of ≥8 points in the National Institutes of Health Stroke Scale (NIHSS) within the first 24 h, was used as a clinical marker of effective reperfusion.
Funding; Spanish Ministry of Science and Innovation (SAF2017- 84267-R), PDC2021-121455-I00, Xunta de Galicia (Axencia Galega de Innovación: IN607A2022–03), Instituto de
Salud Carlos III (ISCIII) (PI17/00540, PI17/01103), ISCIII/PI21/01256/Co-financed by the European Union, Spanish Research Network on Cerebrovascular Diseases RETICS-INVICTUS PLUS (RD16/0019/0001 and RD16/0019/0003), RICORS-ICTUS (Cerebrovascular diseases) RD21/0006/0003 and RD21/0006/0011. DTS/00103 (Desarrollo Tecnológico en Salud del ISCIII) M. BazarraBarreiros is a PFIS Researcher (FI22/00200) of Instituto de Salud Carlos III. T. Sobrino (CPII17/00027), F. Campos (CPII19/00020) and R. Iglesias-Rey (CP22/00061) from the Miguel Servet Program of Instituto de Salud Carlos III. Sponsors did not participate in the study design, collection, analysis, or interpretation of the data, or in writing the report.
Clonic masseter movements as presentation of focal motor status epilepticus
Lambea-Gil Á, Fernández-Vidal JM, Barguilla A et al. Seizure. 2024 Feb 24;117:159-160. doi: 10.1016/j.seizure.2024.02.018. Online ahead of print. PMID: 38422596
Basilar web and basilar fenestration: a case report
Fernández-Vidal JM, Guasch-Jiménez M et al. Neurologia (Engl Ed). 2024 Mar;39(2):209-210. doi: 10.1016/j.nrleng.2024.01.010. Epub 2024 Feb 1. PMID: 38307414
Effect of the Factor XIa Inhibitor Asundexian According to Baseline Infarct Pattern and on MRI Covert Infarct Outcomes
Smith EE, Shoamanesh A, Xu L, Heenan L et al. Stroke. 2024 Feb;55(2):392-402. doi: 10.1161/STROKEAHA.123.043198. Epub 2024 Jan 4. PMID: 38174569