First-in-human phase I clinical trial of a TLR4-binding DNA aptamer, ApTOLL: Safety and pharmacokinetics in healthy volunteers

Hernández-Jiménez M, Martín-Vílchez S, Ochoa D, Mejía-Abril G et al. Mol Ther Nucleic Acids. 2022 Mar 9;28:124-135. doi: 10.1016/j.omtn.2022.03.005. eCollection 2022 Jun 14. PMID: 35402075

https://pubmed.ncbi.nlm.nih.gov/35402075/