Publicaciones

Status of neurosonology in Spain. A study from the Spanish Society of Neurosonology (SONES)

Rodríguez-Pardo J, Carneado-Ruiz J, Martínez-Martínez M et al. Neurologia (Engl Ed). 2025 Jul-Aug;40(6):548-557. doi: 10.1016/j.nrleng.2025.06.003. Epub 2025 Jun 21. PMID: 40550309

https://pubmed.ncbi.nlm.nih.gov/40550309/

Abstract: Stroke patients have shown low reward sensitivity, which is a transdiagnostic dimension that defines the extent to which a person actively pursues rewarding stimuli. Low reward sensitivity has been related to depression and dysregulation of the frontostriatal network. To date, studies have addressed this dimension in heterogenic stroke lesions and the underlying mechanisms of frontostriatal stroke patients are still unknown. This study included 54 participants (32 chronic frontostriatal stroke patients and 22 healthy controls). Reward sensitivity was assessed using the probabilistic reversal learning task. Depressive symptoms were measured with the Adult Self-Report, and resting-state functional connectivity (rsFC) was examined using functional near-infrared spectroscopy (fNIRS) in prefrontal, motor, and parietal cortices. Group differences and predictors of reward sensitivity were analyzed using Bayesian ANCOVA and multiple regression models. Stroke patients displayed lower reward sensitivity, higher depressive problems, and lower resting-state functional connectivity between the right orbitrofrontal cortex and the left dorsolateral prefrontal cortex, the right orbitrofrontal cortex and the right dorsolateral prefrontal, and the right dorsolateral prefrontal cortex and right premotor cortex and supplementary motor area. In stroke patients, lower reward sensitivity was predicted by higher depressive problems and lower resting-state functional connectivity between the right dorsolateral prefrontal cortex and the right premotor cortex and the right supplementary motor area. This work showed the relevance of reward sensitivity in frontostriatal post-stroke patients and its relationship with depression, and supports

Funding: Funding for open access publishing: Universidad de Almería/ CBUA. This work was supported by the Ministry of Science, Innovation and Universities (grant numbers PID2019-108423RB-100 and PID2023-147063 NB-I00), the Carlos III Institute of Health (grant number RICORS-ICTUS; RD21/0006/0010) and PPIT-UAL, Junta de Andalucía-ERDF 2021–2027. Objective RSO1.1. Programme: 54.A.

 

Point-of-care ultrasound for transient ischemic attack assessment in transient ischemic attack clinics: Consensus document of the Spanish Society of Neurosonology

Amaya-Pascasio L, Rodríguez-Pardo de Donlebún J et al. Neurologia (Engl Ed). 2025 Jun;40(5):473-482. doi: 10.1016/j.nrleng.2025.04.006. PMID: 40523715

https://pubmed.ncbi.nlm.nih.gov/40523715/

Abstract: In recent years, there has been increasing recognition of the benefits offered by rapid-access transient ischemic attack (TIA) clinics for the early assessment of patients with suspected TIA. These clinics, designed to deliver specialized diagnoses and treatments, play an important role in mitigating the risk of stroke recurrence. Most of these clinics benefit from using ultrasound diagnostic imaging conducted by qualified neurologists, which guides the treatment and management of TIA patients. This consensus document, developed by a working group from the Spanish Society of Neurosonology, introduces a novel concept for point-of-care ultrasound (POCUS), specifically focusing on optimizing the diagnostic process for TIA patients in the outpatient setting. The aim is to encourage experienced neurovascular clinicians to adopt a standardized, disease-oriented POCUS that can identify ultrasonographic findings related to the underlying cause of the TIA. Additionally, the document seeks to centralize the recommended diagnostic evaluations for TIA patients. By doing so, the goal is to optimize the diagnostic workup and subsequent treatment performed by the neurologist, fostering a more cohesive and effective approach to managing TIA cases.

Funding: This work is part of the Spanish Health Outcomes-Oriented Cooperative Research Networks (RICORS-ICTUS), Instituto de Salud Carlos III (Carlos III Health Institute), Ministerio de Ciencia e Innovación (Ministry of Science and Innovation), RD21/0006/0010 (Torrecardenas University Hospital).

Lower reward sensitivity in frontostriatal stroke: Infuence of depression and resting‑state functional connectivity

Sánchez-Kuhn A, Fernández-Martín P, Rodríguez-Herrera R et al. Cogn Affect Behav Neurosci. 2025 Jun 6. doi: 10.3758/s13415-025-01318-9. Online ahead of print.PMID: 40481315

https://pubmed.ncbi.nlm.nih.gov/40481315/

Abstract: Stroke patients have shown low reward sensitivity, which is a transdiagnostic dimension that defnes the extent to which a person actively pursues rewarding stimuli. Low reward sensitivity has been related to depression and dysregulation of the frontostriatal network. To date, studies have addressed this dimension in heterogenic stroke lesions and the underlying mechanisms of frontostriatal stroke patients are still unknown. This study included 54 participants (32 chronic frontostriatal stroke patients and 22 healthy controls). Reward sensitivity was assessed using the probabilistic reversal learning task. Depressive symptoms were measured with the Adult Self-Report, and resting-state functional connectivity (rsFC) was examined using functional near-infrared spectroscopy (fNIRS) in prefrontal, motor, and parietal cortices. Group diferences and predictors of reward sensitivity were analyzed using Bayesian ANCOVA and multiple regression models. Stroke patients displayed lower reward sensitivity, higher depressive problems, and lower resting-state functional connectivity between the right orbitrofrontal cortex and the left dorsolateral prefrontal cortex, the right orbitrofrontal cortex and the right dorsolateral prefrontal, and the right dorsolateral prefrontal cortex and right premotor cortex and supplementary motor area. In stroke patients, lower reward sensitivity was predicted by higher depressive problems and lower resting-state functional connectivity between the right dorsolateral prefrontal cortex and the right premotor cortex and the right supplementary motor area. This work showed the relevance of reward sensitivity in frontostriatal post-stroke patients and its relationship with depression, and supports the resting-state functional connectivity measurement for characterizing abnormalities in connectivity in stroke patients

Funding for open access publishing: Universidad de Almería/ CBUA. This work was supported by the Ministry of Science, Innovation and Universities (grant numbers PID2019-108423RB-100 and PID2023-147063 NB-I00), the Carlos III Institute of Health (grant number RICORS-ICTUS; RD21/0006/0010) and PPIT-UAL, Junta de Andalucía-ERDF 2021–2027. Objective RSO1.1. Programme: 54.A.